Speakers:
Health Innovation Kent Surrey Sussex; Chief Officer, NHS Health Innovation Network, UK
Hatim is Chief Executive Officer for Health Innovation Kent Surrey Sussex, part of the NHS Health Innovation Network. Alongside this role, he continues to practice as a General Practitioner.
In 2018, Hatim was appointed National Medical Directors Clinical Fellow to Professor Wendy Reid by the Faculty of Medical Leadership and Management. His key achievements were co-author and member of the Sir Keith Pearson Commission into NHS Staff and Learner Mental Health and co-founding the ‘Topol Programme for Digital Health Fellowships’ launched by Secretary of State for Health and Social Care in 2019. He later became the National Clinical Lead for AI and Digital Workforce at NHS England providing clinical leadership to the NHS Digital Academy and leading on AI in the NHS’s historic Long Term Workforce Plan.
Hatim studied Medicine at the prestigious Barts and the London School of Medicine and Dentistry, going on to complete a Masters in Sports and Exercise from the University of South Wales, and a Postgraduate Diploma in Digital Health Leadership from Imperial College London. Hatim holds Membership of the Faculty of Clinical Informatics and the Royal College of General Practitioners, as well as Fellowship of Advance Higher Education.
Hatim has been a Senior Lecturer at Brunel University London, supporting the Physician Associate MSc and development of Brunel Medical School. Hatim is a Honorary Senior Lecturer at Keele University, working with European partners to develop a Masters in Explainable AI in healthcare management. Hatim is also a member of the National Institute for Health and Care Excellence Technology Appraisals Committee, and the Coalition for Health AI Steering Committee.
Hatim is an advocate for safe, ethical and responsible digital and AI transformation and ensuring workforce preparedness for new innovations and technologies in health and care. He regularly speaks internationally and has contributed to the publication of academic papers and white papers spanning workforce, education reform, primary care, digital health and AI.
Outside of work Hatim enjoys travelling and football, and you will likely find him touring England’s best restaurants with his family.
University of Bonn, Bonn, GERMANY
Shadi Albarqouni is a Palestinian-German Professor of Computational Medical Imaging Research. He received his B.Sc. and M.Sc. in Electrical Engineering from the IU Gaza, Palestine, in 2005, and 2010, respectively. In 2012, he received the DAAD research grant to pursue his Ph.D. at the Chair for Computer Aided Medical Procedures (CAMP), Technical University of Munich (TUM), Germany. During his Ph.D., Albarqouni worked with Prof. Nassir Navab on developing machine learning algorithms to handle noisy labels, coming from crowdsourcing, in medical imaging. His AggNet paper, published at the Special Issue on Deep Learning at the IEEE Transaction on Medcial Imaging (IF: 10.048), was among the first ones on Medical Imaging with Deep Learning and has been featured as the top downloaded article for a couple of years at IEEEXplore.
Albarqouni worked as a Senior Research Scientist & Team Lead at CAMP leading the Medical Image Analysis (MedIA). Together with his team addressed the common challenges concern the nature of medical data, namely heterogeneity, severe class-imbalance, few amounts of annotated data, inter-/intra-scanners variability (domain shift), inter-/intra-observer disagreement (noisy annotations). In 2019, Albarqouni received the prestigious P.R.I.M.E. fellowship for a one-year international mobility, where he worked as a Visiting Scientist at the Department of Information Technology and Electrical Engineering (D-ITET) at ETH Zürich, Switzerland. He worked with Prof. Ender Konukoglu on Modeling Uncertainty in Medical Imaging, in particular, the one associated with inter-/intra-raters variability. Afterwards, Albarqouni worked as a Visting Scientist with Prof. Daniel Rueckert at the Department of Computing at Imperial College London, United Kingdom.
Since Nov. 2020, Albarqouni has been appointed as an AI Young Investigator Group Leader at Helmholtz AI. The aim of Albarqouni’s Lab. is to develop innovative deep Federated Learning algorithms that can distill and share the knowledge among AI agents in a robust and privacy-preserved fashion. Since Jan. 2022, Albarqouni has been appointed as a W2 Professor of Computational Medical Imaging Research at the Faculty of Medicine, University of Bonn.
Albarqouni has more than 100 peer-reviewed publications in both Medical Imaging Computing and Computer Vision published in high impacted journals and top-tier conferences. He is an active member of MICCAI, BMVA, IEEE EMBS, IEEE CS, and ESR society. Recently, Albarqouni has been elected as a member for the European Lab for Learning and Intelligent Systems (ELLIS), the Arab German Young Academy (AGYA), and the Higher Council for Innovation and Excellence in Diaspora (HCIE). Since 2015, he has been serving as a PC member for a couple of MICCAI workshops, e.g., COMPAY, DART, DCL, FAIR among others. Since 2019, Albarqouni has been serving as an Area Chair in Advance Machine Learning Theory at MICCAI. Recently, he has been serving as a Program Co-Chair at MIDL’22 in Swizterland, and as an Organizing Committee Member at ISBI’22 in India, MICCAI’24 in Morocco. His current research interests include Interpretable ML, Robustness, Uncertainty, and Federated Learning. He is also interested in Entrepreneurship and Startups for Innovative Medical Solutions with limited resources.
Necker Enfants Malades University Hospital, APHP, Paris, France
Guillaume Canaud is a MD, PhD working at hôpital Necker Enfants Malades (Paris). He did his medical school in Montpellier and moved to Paris in 2002 to perform his Residency in Nephrology (2002 to 2007). He became Senior Resident in the Renal Division of Necker (Prof. Legendre) from 2007 to 2012. Concurrently, he spent four years from to 2008 to 2012 in the laboratory of Dr. Fabiola Terzi (INSERM U1151, Necker Hospital) to achieve his PhD degree in molecular and cellular biology. Then, he joined the Joseph Bonventre’s Laboratory (Harvard Medical School, Boston, USA) from 2012 to 2014 to achieve a postdoc. He came back to Christophe Legendre’s team with a faculty position (Associate Professor) and built his own group of research dedicated to translational medicine. He obtained an European Research Council starting grant (2015) for his kidney research project, an ERC Proof of Concept Grant for his translational research (2016) and an ERC Consolidator (2020) dedicated to the understanding of PIK3CA related disorders. Guillaume is now full professor at the Université Paris Cité /Hôpital Necker Enfants Malades and is working specifically on rare disorders involving the RAS/PIK3CA/AKT/mTOR pathways. He has created the Translational Medicine and Targeted Therapies Unit at Necker Enfants Malades.
Very recently, Guillaume and his group, identified and reported in Nature a very promising therapeutic for patients with a rare genetic disorder called PIK3CA-Related Overgrowth Syndrome (PROS). Guillaume and his group pushed the clinical development of this drug for patient with PROS. Three clinical trials were launched since 2019 and led to the US FDA accelerated approval on April 6th 2022 of alpelisib for patients with PROS aged of at least 2 years old.
He published as a first or last author in leading medical and scientific journals such as Nature, The New England Journal of Medicine, Nature Medicine, J Exp Med, Science Translational Medicine or Proceedings of the National Academy of Sciences USA. He received several awards including the 2018 Prize Jean Lecocq of the French Academy of Sciences, the 2019 Prize Eloi Collery of the French Academy of Medicine, the 2019 Ville de Paris Jean Hamburger Prize, the 2021 Unsolicited International Triennial Gagna A. & Ch. Van Heck Prize for Incurable Diseases, the 2022 Robert Schobinger Award from the International Society for the Study of Vascular Anomalies and the Prix Galien 2022.
Mayo Clinic Florida – Jacksonville, Florida, USA
Dr. Fouad T. Chebib, MD, FASN, is a nephrologist and assistant professor of Medicine at Mayo Clinic Florida. After obtaining his undergraduate degree from the American University of Beirut, and his medical degree from the University of Balamand, Lebanon, Dr. Chebib pursued further specialization through a postdoctoral research fellowship in molecular nephrology and ion channels at Harvard University’s Alper Lab. His journey continued with a residency in internal medicine at Saint Elizabeth Medical Center, Tufts University, and a nephrology fellowship at Mayo Clinic, where he also spent two years as a Mayo Clinic Scholar under the mentorship of Dr. Vicente Torres.
Dr. Chebib’s commitment to combating Polycystic Kidney Disease (PKD) has been evident through his clinical focus and research endeavors aimed at understanding cyst formation in ADPKD and identifying targeted treatments. His efforts have contributed to the establishment of the Tolvaptan Clinic at Mayo Clinic, the first FDA-approved drug to slow PKD progression. An innovator in his field, Dr. Chebib holds a patent for his work and actively participates in major ADPKD clinical trials.
Dr. Chebib is the lead author on the US consensus guidelines on the use of Tolvaptan in ADPKD and has been an invited speaker at numerous national meetings, including the American Society of Nephrology and National Kidney Foundation, as well as various academic institutions. He is a member of the workgroup for the KDOQI US commentary on the KDIGO Clinical Practice Guidelines on ADPKD, where his expertise contributes to shaping clinical practices and guidelines that impact patients globally. Dr. Chebib’s interests includes establishing an individualized approach and precision in diagnosis and prediction of outcomes in ADPKD by leveraging advances in artificial intelligence.
As director of both the PKD Center of Excellence and the Discovery and Translational PKD Research lab at Mayo Clinic Florida, Dr. Chebib spearheads innovative research into novel therapeutic targets for PKD. His active engagement with the PKD Foundation’s Education Advisory Panel and Center of Excellence advisory board further highlights his unwavering commitment to eradicating PKD through education and research.
Centre for Medical Science and Technology Studies, University of Copenhagen, Denmark
Mie S. Dam is an Assistant Professor in the Centre for Medical Science and Technology Studies, the University of Copenhagen. Through ethnographic fieldwork in animal-, cell-, and genomic laboratories and at public hospitals, her research addresses the ethical, social, and political aspects of precision oncology and its translation across laboratory, clinic, and patient lives. Trained as a MSc in Public Health, Mie S. Dam strives to weave together specific empirical observations with the broader social and public spheres in which biomedical technologies and healthcare practices develop. Her work has been published and recognized in international high-ranking social science journals.
Boston Children's Hospital – Harvard Medical School – Boston, USA
Dr. Grant is the Käthe Beutler, MD Harvard Professor of Pediatrics and Professor of Radiology at Harvard Medical School. She is the founding Director of the Fetal Neonatal Neuroimaging and Developmental Science Center (FNNDSC) in the Departments of Medicine and Radiology, the Director of Faculty Affairs in the Department of Radiology, the Direct of Research for the Division of Maternal-Fetal Medicine and Surgery and a clinical neuroradiologist at Boston Children’s Hospital.
Dr. Grant founded the FNNDSC in 2009 to develop and optimize tools and analysis streams to better detect and understand both normal and abnormal brain physiology and development. The primary goal is to provide phenotypic and mechanistic information that enables optimization of cognitive, behavioral, and neurological outcomes in children with a focus on fetuses, neonates, infants, and toddlers. Three modalities are being developed in the FNNDSC: Magnetic Resonance Imaging (MRI), Magnetoencephalography (MEG) and quantitative Near Infrared Spectroscopy (qNIRS). She leads a team of MR physicists and engineers doing pulse sequence development and novel MRI analysis at the forefront of fetal and placental MRI. Her team build a novel pediatric specific MEG system that is now FDA approved and provides clinical services for presurgical evaluation of infants and toddlers with epilepsy.
She is a pioneer of frequency domain NIRS (FDNIRS) and diffuse correlation spectroscopy (DCS) which provides quantitative bedside measures of cerebral blood flow and oxygen consumption. To support the computational needs of complex data analysis, her team has developed a sophisticated computational infrastructure in collaboration with RedHat to support deep-learning approaches on large datasets and real time data analysis.
The FNNDSC currently has over 60 members with 17 faculty and 6 postdoctoral students. Dr. Grant is a Senior Fellow of the International Society of Magnetic Resonance in Medicine (ISMRM) and sits on the Board of Scientific Counselors for National Institute of Child Health and Human Development. In 2021 she received the Outstanding Contributions in Research Award from the American Society of Neuroradiology and in 2022 she received the Gold Medal Award from the American Society of Pediatric Neuroradiology. She is currently PI/MPI of 6 NIH grants and her center has over $40M of active funding.
Boston Children's Hospital – Harvard Medical School – Boston, USA
Peter Laussen, MBBS, FANZCA, FCICM, is the Executive Vice President of Health Affairs at Boston Children’s Hospital. An esteemed leader in hospital care, Dr. Laussen oversees the medical delivery system and helps craft the vision for continued growth in technology and pediatric care. He partners with leadership across the hospital on a full range of research, clinical, academic, operational, and strategic issues, while also caring for patients as an Attending in the Cardiac Intensive Care Unit.
Dr. Laussen has been a member of the Boston Children’s team for more than two decades. In 2002, he was appointed Chief of the Division of Cardiovascular Clinical Care and the Dolly D. Hansen Chair in Pediatric Anesthesia. During his first tenure at Boston Children’s, Dr. Laussen was instrumental in the development of “T3” (Tracking, Trajectory, and Triggering), a web-based early warning system that helps ICU staff assess the patient’s physiologic state at their bedside. He also co-founded “Risky Business,” the groundbreaking series of conferences focusing on risk management, patient safety, and safety awareness.
Following his first years of service at Boston Children’s, Dr. Laussen joined the Hospital for Sick Kids (SickKids) in Toronto, as Chief of the Department of Critical Care Medicine, where he oversaw one of the preeminent pediatric critical care programs in the world. Dr. Laussen also served as Associate Senior Scientist in Child Health and Evaluative Sciences at the SickKids Research Institute, where he built one of the largest data science programs in pediatric critical care in the world.
Dr. Laussen returned to Boston Children’s in May 2020, taking on his current role as Executive Vice President of Health Affairs. His research and educational focus are centered on cardiac critical care and anesthesia, and he continues to pass on his knowledge and expertise in the field by serving as an Adjunct Professor of Anesthesia at the University of Toronto, and a full Professor of Anesthesia at Harvard Medical School.
Dr. Laussen received his medical degree from Melbourne University Medical School, in Melbourne, Australia, and fellowships in anesthesia and pediatric critical care medicine. Throughout his career, Dr. Laussen has achieved significant success in recruitment strategies for new faculty, reduction of Serious Safety Events, development of a sustainable research structure, and growth of world-renowned training programs.
Maine Health Institute for Research in Scarborough, Maine, USA
Dr. Nadeau is internationally recognized for his work on mouse models of human disease. He has pioneered comparative genomics, genetics and systems studies of mouse models of human disease, with an emphasis on transgenerational epigenetic effects on metabolism and cancer, and most recently on phenotypic ‘noise’ in metabolic systems. His work is contributing to a revolution in the ways that we understand inheritance of phenotypic variation and disease susceptibility. He is a faculty Scientist III at Maine Health Institute for Research in Scarborough, Maine. He is the former chair and James H, Jewell Professor of Genetics at Case Western Reserve University School of Medicine. He is the founding director of the Mouse Genome Informatics Project and the Mouse Genome Database, founding director of the Ohio GI Cancer Consortium, and founding editor of two research journals, one of which (Systems Biology and Medicine) won the American Publishers Awards for Professional & Scholarly Excellence (PROSE) top award for outstanding scholarly work in all disciplines of the arts and sciences. The Smithsonian Museum deposited in their permanent collection a copy of the MGI-MGD software as an example of Innovation in Information Technology. Among his recognitions are an National Institutes of Health Pioneer Award and election as Fellow of the American Association for the Advancement of Science.
Centre for Medical Science and Technology Studies, University of Copenhagen, Denmark
Mette N. Svendsen is a Professor of Medical Anthropology in the Centre for Medical Science and Technology Studies, the University of Copenhagen. She works at the forefront of the integrated study of medicine, health, and society. Since 2017, she has headed the research project MeInWe, which investigates the ethical, organizational, and legal challenges of precision medicine in contemporary healthcare (www.meinwe.ku.dk). She has an extensive publication record in leading international journals and is the author of the book Near Human: Border Zones of Life, Species, and Belonging published by Rutgers University Press.
University of Bern, Bern, Switzerland
Mark A. Rubin, MD, Professor, Principal Investigator, and Director of the Department for BioMedical Research (DBMR), University of Bern, Switzerland. Prof. Mark Rubin is a recognized world-renown leader in prostate cancer genomics and pathology, and precision medicine. Dr. Rubin’s laboratory led a series of landmark studies defining distinct molecular features of prostate cancer, revealing pathways that are perturbed and drive different types of this cancer. Furthermore, Prof. Rubin has translated many of his genomic discoveries into clinical tests that are currently patented and standardly used in the diagnosis and treatment of prostate cancer. Prof. Rubin founded the Englander Institute for Precision Medicine and, more recently, the Bern Center for Precision Medicine (BCPM).
Necker University Hospital, Paris, FRANCE
Manuel, MD, PhD is a Professor of Paediatrics at the Reference Centre for Inborn Errors of Metabolism at Necker University Hospital and Imagine Institute, Paris. After an undergraduate degree in Biochemistry and a residency in Paediatrics, he completed a PhD in mitochondrial biology, under the supervision of Dr Pierre Rustin at the University of Paris Descartes. He then was a post-doctoral fellow at Dr Jerry Vockley’s laboratory at the University of Pittsburgh, USA. His clinical research interests include mitochondrial energy metabolism and homocysteine metabolism disorders for which he is a partner in the European collaborative network EHOD. His basic research projects include mitochondrial energy metabolism within the mitochondrial disease genetics lab directed by Agnès Rötig in the Paris Necker Imagine Institute. Manuel is a partner of the European ERA PerMed JTC2019 projects PerMiM focusing on personalized medicine in mitochondrial disease coordinated by Dr Holger Prokisch (Helmholtz Zentrum München, Germany). Gene therapies for maple syrup urine disease in mouse is the other research project for which Manuel’s research group has obtained nice preclinical results paving the way to potential future clinical trials in patients.
Manuel is coordinating the national reference centre for mitochondrial diseases (CARAMMEL) at Necker hospital and is the chair of the Society for the Study of Inborn Errors of Metabolism (SSIEM).
Mälardalen University, Västerås, SWEDEN
Dr. Sarah Wamala Andersson is a distinguished thought leader in digital health and currently serves as a Professor of Health and Welfare Technology at Mälardalen University. Her research focus on the real-world implementation of AI solutions and digital health technologies within healthcare and social care systems. She evaluates policies and reimbursement models, and she generates evidence to demonstrate the value and effectiveness of digital health technologies, particularly through the lenses of equity, ethics, and sustainability.
In her academic role, she is also involved in mentoring, teaching and supervising Master’s and PhD students in areas related to digital transformation in health and social care.
Sarah holds a PhD in Medical Sciences from Karolinska Institutet and a Master’s degree in Biostatistics from Stockholm University. She has also completed postdoctoral studies at the Wellington School of Medicine in New Zealand and the Stanford Executive Program in the USA. Additionally, she has studied economics at Makerere University and epidemiology in both UK and USA.
Her career includes executive leadership roles, such as serving as the Swedish Government as Director General of the Swedish Public Health Institute and as a Professor of Health Policy at Karolinska Institutet. She also has experience in the pharmaceutical industry, having worked as a Principal Real-World Scientist at a global pharmaceutical company.
Sarah is widely published and leads several international research initiatives. She is a frequent keynote speaker at global conferences, where she shares her insights on digital health and the future of healthcare systems.
University Hospital Heidelberg, Heidelberg University, Heidelberg, GERMANY
Eva Winkler has two professional careers: in Medical Ethics and in Oncology. She is the Head of the Section for Translational Medical Ethics, University Hospital Heidelberg (UKHD), Heidelberg University. She is also a member of the Board of Directors of the National Center for Tumor Diseases, Heidelberg and works as a senior physician and specialist in hematology/oncology in the Department of Medical Oncology at UKHD.
Eva Winkler holds a doctorate in cancer research from Heidelberg University / German Cancer Research Center (DKFZ) and a PhD in medical and health ethics from the University of Basel, Switzerland (with distinction). She spent two years of her medical ethics training as part of two fellowships in the Division of Medical Ethics at Harvard Medical School and as a faculty fellow at the Center for Ethics and the Professions at Harvard University / Kennedy School of Government.
Eva Winkler’s research focuses on empirically informed applied ethics. Areas of research are:
- Research Ethics: ethical questions of precision medicine, genome sequencing and editing; overall ethical questions of translation between research and healthcare
- Clinical Ethics: especially decisions at the end of life, organizational ethics
- Public Health Ethics: resource allocation, secondary use of health data
As vice president of the Academy for Ethics in Medicine (German Society for Ethics in Medicine) and elected chairwoman of the Central Ethics Commission of the Federal Medical Association (ZEKO) Eva Winkler is committed to further advance and professionalize medical ethics and shape the discipline and its contribution to research, the healthcare system and politics.
Eva Winkler is an invited expert in important national, European and global initiatives for research-enabling infrastructures. She is the Ministry of Health appointed representative for the European Initiatives on Genomic Data Infrastructure (GDI) and 1+Million Genomes (EU) and member of the Scientific Advisory Board of the National Cohort Study (NAKO) and the Cancer Registries united at the Robert Koch Institute (RKI).
Additionally, Eva Winkler is the scientific director and spokesperson for EURAT (interdisciplinary platform for Ethical and Legal Aspects of Translational Medicine) in Heidelberg (www.eurat.info).